Identifying the cellular signaling signals that tell HSPBs to move (translocate) to the OMM immediately following a heat shock or stressful cellular event.
: Her current work investigates the dual role of HSPBs in mitochondria. Under normal conditions, these proteins prevent aggregation within the mitochondrial intermembrane space, but they translocate to the outer membrane during heat shock or due to specific mutations. Charcot-Marie-Tooth (CMT) Disease ayesha kiran mendes
Her research tackles some of the most challenging aspects of cellular biology: The Protein Protectors Identifying the cellular signaling signals that tell HSPBs
, reflecting a diverse set of interests that extend into the arts and collaborative storytelling. Her research aims to understand how mutations or
Ayesha has embraced her son’s diverse fanbase, often engaging with fans (known as "Mendes Army") on social media. She is known for her warm, maternal presence, often posting birthday tributes to Shawn and Aaliyah that reveal a home life filled with laughter, baking, and normal suburban routines.
Her research aims to understand how mutations or dysfunctions in these processes lead to peripheral neuropathies, which are conditions affecting the nerves outside the brain and spinal cord. Professional Background
: Ayesha’s work has helped uncover a "dual role" for these proteins, showing how they move between the mitochondrial intermembrane space and the outer membrane in response to stress like heat shock. Deciphering Disease